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4,5‐Bis(chloromethyl)uracil
Author(s) -
Greenwald Richard B.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130546
Subject(s) - chemistry , uracil , nucleophile , combinatorial chemistry , organic chemistry , catalysis , dna , biochemistry
A one‐step synthesis of 4,5‐bis(chloromethyl)uracil from readily available starting materials has been accomplished. This substance is a stable, crystalline solid which undergoes facile nucleophilic attack to produce various di‐substituted uracil derivatives.
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