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Nitrofuranyl heterocycles. XIII N ‐methyl‐3‐methylthio‐5‐(5‐nitro‐2‐furanyl)‐1 H ‐1,2,4‐triazoles
Author(s) -
Benjamin Louis E.,
Snyder Harry R.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130540
Subject(s) - chemistry , nitrofuran , nitro , antimicrobial , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , alkyl , genetics , biology
A continuing search for new nitrofurans which might possess useful antimicrobial activity led to the synthesis of several 3‐mercapto‐5‐(5‐nitro‐2‐furanyl)‐1 H ‐1,2,4‐triazoles and their methylated derivatives. This paper describes the preparation of these compounds together with proof of structure of the N ‐methylated products.
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