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Model reactions in the pseudonucleoside series
Author(s) -
Fissekis John D.,
Lehnberg James W.,
Sweet Frederick,
Lipnick Robert L.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130452
Subject(s) - chemistry , thiourea , bromine , urea , base (topology) , condensation , propionate , organic chemistry , series (stratigraphy) , medicinal chemistry , mathematical analysis , physics , mathematics , thermodynamics , paleontology , biology
A series of pseudonucleoside analogs has been prepared from the base‐catalyzed condensation of methyl 3,3‐dimelhoxy‐2‐(telrahydrofuran‐2‐yl)propionate with urea and thiourea, followed by cyclization(s) with acid, bromine and peroxyformic acid. Some of their reactions which lead to other model pseudonucleosides are reported.