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A new fused tetrazole ring system: Tetrazolo [1,5‐b] isoquinoline
Author(s) -
Hajós G. Y.,
Messmer A.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130436
Subject(s) - chemistry , tautomer , tetrazole , isoquinoline , ring (chemistry) , nuclear magnetic resonance spectroscopy , stereochemistry , computational chemistry , organic chemistry
Abstract Tetrazolo[1,5‐α]isoquinoline ( 5b ), the linear benzologue of tetrazolopyridine, has been prepared. In contrast to the angular isomers ( 1b and 2 ) the linear system exists in solution predominantly in the tautomeric azido‐form ( 5a ) and even in the crystalline state contains a certain amount of 3‐azidoisoquinoline ( 5a ). The tautomeric equilibrium in solution was studied by nmr spectroscopy.