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Ethylenimine derivatives of some 1,2,4‐triazines
Author(s) -
Keen Brian T.,
Krass Dennis K.,
Paudler W. W.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130423
Subject(s) - chemistry , medicinal chemistry , value (mathematics) , stereochemistry , combinatorial chemistry , mathematics , statistics
The first 3‐ethylenimino‐1,2,4‐triazines ( 9 ) have been synthesized from the corresponding 3‐(β‐chloroethyl)amino‐1,2,4‐triazines ( 8 ). In addition some 2,3‐dihydroimidazo[1,2‐ b ]‐1,2,4‐triazines and imidazo[1,2‐ b ]‐1,2,4‐triazines were obtained. The stability, properties and potential therapeutic value of these compounds are discussed.