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Formyl substituted phenazine 5,10‐dioxides
Author(s) -
Edwards M. L.,
Bambury R. E.,
Kim H. K.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130352
Subject(s) - phenazine , chemistry , antibacterial activity , in vitro , in vivo , combinatorial chemistry , organic chemistry , bacteria , biochemistry , genetics , microbiology and biotechnology , biology
Two new formyl‐substituted phenazine 5,10‐dioxides were prepared, 2‐formylphenazine 5,10‐dioxide and 7‐hydroxy‐2‐phenazinecarboxaldehyde 5,10‐dioxide. Nitrones of these aldehydes were prepared as potential antibacterial agents but evaluation in vitro and in vivo did not disclose significant antibacterial activity.