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Rearrangement of ethyl 2‐(3‐amino‐4‐pyridinyl)hydrazinecarboxylate hydrochloride to 1‐amino‐1 H ‐imidazo[4,5‐ c ]pyridin‐2(3 H )one hydrochloride
Author(s) -
Wright George C.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130336
Subject(s) - chemistry , hydrochloride , medicinal chemistry , stereochemistry , organic chemistry
In a study of the synthesis (unsuccessful) of pyrido[3,4‐ e ]‐as‐triazino‐3 (4 H )one (6) , the acidification of 2‐(3‐amino‐4‐pyridyl)hydrazinecarboxylate hydrochloride (8) unexpectedly gave 1‐amino‐1 H ‐imidazo[4,5‐ c ]pyridin‐2(3 H ) one hydrochloride (10). The isolation and characterization of 10 has been described.

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