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N ‐alkoxydipyrrylmethenes
Author(s) -
Abramovitch R. A.,
Amarnath V.,
Kress R.,
Molina G.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130309
Subject(s) - chemistry , nitrile , bromide , alkylation , hydrogen bromide , condensation , aldehyde , medicinal chemistry , hydride , hydrogen , organic chemistry , catalysis , bromine , physics , thermodynamics
2‐Cyano‐ N ‐hydroxypyrroles are O‐alkylated and the nitrile function reduced to the corresponding aldehyde with diisobutylaluminum hydride. Condensation with pyrroles in the presence of hydrogen bromide gives the difficultly purified N ‐alkoxydipyrrylmethanes.
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