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The preparation of heterocyclic materials from 2‐isocyanatobenzoyl chloride and difunctional nucleophiles
Author(s) -
Beam Charles F.,
Heindel Ned D.,
Chun Maria,
Stefanski Anthony
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130249
Subject(s) - chemistry , nucleophile , reagent , chloride , thioacetamide , organic chemistry , medicinal chemistry , polymer chemistry , catalysis , biochemistry
2‐Isocyanatobenzoyl chloride was treated with difunctional nucleophiles such as o ‐phenylenediamine, 1,8‐diaminonaphthalene, o ‐aminothiophenol, and thioacetamide. The diaminonucleophiles gave intermediates which were thermally cyclized, and the other nucleophilic reagents gave heterocyclic materials directly.