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Reaction of Sulfene wild Heterocyclic N,N ‐Disubstituted α‐Aminomethylene Ketones IV. Synthesis of 3,4‐Dihydro‐5 H ‐[1]benzothiopyratio [3,4‐ e ]‐1,2‐oxathiin and 2,3,6,7‐Tetrahydro‐5 H ‐thiopyrano[3,4‐ e ]‐1,2‐oxathiin Derivatives
Author(s) -
Sche Pietro,
Mosti Luisa,
Bignardi Gaetano
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130206
Subject(s) - chemistry , pyrazole , medicinal chemistry , stereochemistry
The reaction of sulfene with N,N ‐disubstituted 3‐aminomethylene‐2,3‐dihydro‐4‐thiochromanones and‐2,3,5,6‐tetrahydro‐4‐thiopyranones gave 1,4‐cycloadducts which are derivatives of new heterocyclic systems, namely 3,4‐dihydro‐5 H ‐[1]benzothiopyrano[3,4‐ e ]‐1,2‐oxathiin and 3,4,7,8‐tetrahydro‐5 H ‐thiopyrano[3,4‐ e ]‐1,2‐oxathiin, respectively. Furthermore, some pyrazole derivatives VII and VIII were prepared from 3‐hydroxymethylene‐2,3‐dihydro‐4‐thiochromanone or 2,3,5,6‐tetrahydro‐4‐thiopyranone and hydrazines.