Premium
Acetylenic ketones. I. Reaction of aroylphenylacetylenes with compounds containing an active methylene group
Author(s) -
Baddar F. G.,
AlHajjar F. H.,
ElRayyes N. R.
Publication year - 1976
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570130202
Subject(s) - chemistry , methylene , sodium ethoxide , sodium cyanide , phenylacetate , medicinal chemistry , cyanide , organic chemistry , aryl , pyran , alkyl , biochemistry , ethanol
Aroylphenylacetylenes reacted with ethyl phenylacetate and benzyl cyanide in the presence of sodium ethoxide to give 6‐aryl‐3,4‐diphenyl‐2 H ‐pyran‐2‐ones (2) and 4‐aroyl‐2,3‐ cis ‐diphenyl‐crotonitriles (11) , respectively. The structure and configuration of the products are based on chemical and spectroscopic evidence.