Unexpected formation of a 10 H ‐Pyrido[2,3‐ h ]pyrazolo[3,4‐ b ]quinoline derivative, a new ring system | Zendy

Crenshaw R. R. | Zendy; Luke G. M. | Zendy; Whitehead D. F. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Unexpected formation of a 10 H ‐Pyrido[2,3‐ h ]pyrazolo[3,4‐ b ]quinoline derivative, a new ring system

Author(s) -

Crenshaw R. R.,

Luke G. M.,

Whitehead D. F.

Publication year - 1976

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570130134

Subject(s) - chemistry , quinoline , ring (chemistry) , anthranilic acid , yield (engineering) , derivative (finance) , medicinal chemistry , stereochemistry , phosphorus , organic chemistry , materials science , economics , financial economics , metallurgy

Treatment of N ‐(1,3‐dimethylpyrazol‐5‐yl)‐4‐anthranilic acid with phosphorus oxychloride gave an intermediate which was condensed with 3‐dimethylaminopropylamine to yield 10,8‐dimethyl‐7‐(3‐dimethylaminopropylamino)‐10 H ‐pyrido[2,3‐ h ]pyrazolo[3,4‐ b ]quinoline (IV). The structure of IV, which represents a previously undescribed ring system, was confirmed by an independent synthesis.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research