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A novel synthesis of dibenzo[ b,f ] [1,4]thiazepin‐11(10 H )one 5,5‐dioxides
Author(s) -
Bennett O. Francis,
Johnson James,
Galletto Sandra
Publication year - 1975
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570120623
Subject(s) - chemistry , liquid ammonia , amide , ammonia , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry
Treatment of thioxanthen‐9‐one 10,10‐dioxides with sodium amide in liquid ammonia provided a novel one‐step conversion to dibenzo[ b,f ][1,4]thiazepin‐11(10 H )one 5,5‐dioxides. Some limitations and a possible mechanism for the reaction are discussed.