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A novel dehydrogenation occurring during the synthesis of the new heterocyclic system 1 H ‐pyrazolo[3,4‐ b ][2,7]naphthyridin‐8‐one
Author(s) -
Winn Martin
Publication year - 1975
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570120316
Subject(s) - chemistry , dehydrogenation , acetic acid , alkyl , medicinal chemistry , combinatorial chemistry , molecule , organic chemistry , catalysis
1,3‐Disubstituted‐5‐aminopyrazoles and N ‐alkyl‐3‐carbethoxy‐4‐piperidones condense in refluxing acetic acid to give 1,3,6‐trisubstituted 4,5‐dihydro‐1 H ‐pyrazolo[3,4‐ b ][2,7]naphthyridin‐8(6 H )ones (a new heterocyclic system) with loss of one molecule of hydrogen.
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