Premium
New routes to the v ‐triazolo[1,5‐ a ]pyridine and pyrazolo[1,5‐ a ]pyridine ring systems
Author(s) -
Tamura Yasumitsu,
Kim JoongHyup,
Miki Yasuyoshi,
Hayashi Hironori,
Ikeda Masazumi
Publication year - 1975
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570120307
Subject(s) - chemistry , pyridine , quinoline , oxime , ring (chemistry) , ketone , amine gas treating , medicinal chemistry , organic chemistry
New routes to the v ‐triazolo[1,5‐ a ]pyridine and pyrazolo[1,5‐ a ]pyridine ring systems are described. Treatment of the N ‐amine salts of 2‐picolinealdehyde oxime or 2‐pyridyl ketone oximes with polyphosphoric acid gave v ‐triazolo[1,5‐ a ]pyridines in fair yields. Treatment of 2‐picolyl ketones or their oximes with O ‐mesitylenesulfonylhydroxylamine produced directly pyrazolo‐[1,5‐ a ]pyridines. These reactions were extended to the quinoline cases.