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Nucleophilic displacement of aromatic fluorine, Part III , indoloquinolines and benzofuranoquinolines
Author(s) -
Walser Armin,
Silverman Gladys,
Flynn Thomas,
Fryer R. Ian
Publication year - 1975
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570120227
Subject(s) - chemistry , quinoline , nucleophile , indole test , benzazepines , fluorine , intramolecular force , medicinal chemistry , nucleophilic aromatic substitution , displacement (psychology) , benzazepine , stereochemistry , nucleophilic substitution , organic chemistry , catalysis , psychology , psychotherapist
Variously substituted indolo[2,3‐c]quinolines, benzofurano[2,3‐c]quinolines and their positional isomers indolo[3,2‐c]quinolines and benzofurano[3,2‐c]quinolines respectively, were prepared from both indole and quinoline derivatives by intramolecular nucleophilic displacement of aromatic fluorine. The formation of an indolo[2,3‐d]benzazepine was also observed.