Premium
Synthesis and properties of 1,4‐dimethylpyridazino[4,5‐ d ] pyridazines
Author(s) -
Adembri G.,
De Sio F.,
Nasi R.,
Scotton M.
Publication year - 1975
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570120116
Subject(s) - chemistry , pyridazine , lithium aluminium hydride , lithium (medication) , hydrazine (antidepressant) , aluminum hydride , medicinal chemistry , organic chemistry , ion , chromatography , medicine , endocrinology , methoxide
Abstract The synthesis and properties of several 1,4‐dimethylpyridazino[4,5‐ d ]pyridazines are described. Treatment of diethyl 3,6‐dimethylpyridazine‐4,5‐dicarboxylate ( 1a ) with lithium aluminium hydride and hydrazine did not afford the expected 1,4‐dimethylpyridazino[4,5‐ d ]pyridazine ( 21b ) but a mixture of compounds 13, 18, 19 , and 20 , whose structures were deduced from spectroscopic data.