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1,2,4‐Triazines. VI. Imidazo[1,2‐ b ]‐ as ‐triazines
Author(s) -
Lalezari I.,
Levy Y.
Publication year - 1974
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570110311
Subject(s) - chemistry , phenylglyoxal , hydrochloric acid , hydrate , medicinal chemistry , organic chemistry , amino acid , biochemistry , arginine
Imidazo[1,2‐ b ]‐ as ‐triazines were obtained in high yields by heating substituted glyoxaldoximes with 1,2‐diaminoimidazoles in the presence of hydrochloric acid. Phenylglyoxal hydrate in a similar reaction afforded a mixture of 2‐ and 3‐diphenyl‐6‐arylimidazo[1,2‐ b ]‐ as ‐triazines. α‐Ketoacids and 1,2‐diaminoimidazoles in the presence of hydrochloric acid afforded 2,6‐disubstituted‐4 H ‐imidazo[1,2‐ b ]‐ as ‐triazin‐3‐ones.
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