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Heterocyclic synthesis with β‐ketosulfoxides IV. Synthesis of 3‐substituted chromones
Author(s) -
Klutchko S.,
Cohen M. P.,
Shavel J.,
Von Strandtmann M.
Publication year - 1974
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570110214
Subject(s) - chemistry , organic chemistry , combinatorial chemistry
A novel synthesis of 3‐(hydroxymethyl)chromones from o ‐hydroxy‐ω‐(methylsulfinyl)acetophenones has been developed. These have been utilized in the synthesis of 3‐formyl, 3‐cyano, 3‐carboxy, 3‐carboxamido, 3‐chloromethyl, 3‐aminomethyl and 3‐methoxymethylchromones.