Premium
1.6‐Naphathyridines II. 2,3‐Distributed derivatives and some new tricyclic ring systems
Author(s) -
Hawes Edwared M.,
Gorecki Dennis K. J.
Publication year - 1974
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570110208
Subject(s) - chemistry , tricyclic , methylene , ring (chemistry) , medicinal chemistry , combinatorial chemistry , stereochemistry , organic chemistry
A number of new 2‐ and/or 3‐substituted 1,6‐naphthyridines were prepared via Friedländer reactiona with 4‐aminonicotinaldehyde and methylene compounds containing α‐ketones, Methylene compounds with two reactive α‐centers were also used. The facile conversion of the 1,6‐naphthyridines into new tricylic ring system is reported.