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Properties of lipoic acid analogs
Author(s) -
Shih Jason C. H.,
Williams Paul B.,
Wright Lemuel D.,
Mccormick Donald B.
Publication year - 1974
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570110203
Subject(s) - dithiolane , chemistry , lipoic acid , thioctic acid , propanoic acid , organic chemistry , chromatography , antioxidant
Two chain‐shortened analogs of lipoic (1,2‐dithiolane‐3‐pentanoic) acid, viz. bisnor‐lipoic (1,2‐dithiolane‐3‐propanoic) and tetranorlipoic (1,2‐dithiolane‐3‐carboxylic) acids, have been chemically synthesized. The ir, uv, pmr, and mass spectroscopic properties and paper, thin‐layer, and column chromatographic mobilities of lipoic acid and its analogs were investigated and are given.