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Synthesis and reactions of 2‐aryl‐3‐(dimethylamino)acroleins
Author(s) -
Coppola Gary M.,
Hardtmann Goetz E.,
Huegi Bruno S.
Publication year - 1974
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570110111
Subject(s) - chemistry , aryl , organic chemistry , combinatorial chemistry , medicinal chemistry , alkyl
The preparation of a number of novel 2‐aryl‐3‐(dimethylamino)acroleins and their hydrolyses to 2‐arylmalondialdehydes is described. Reactions of the acroleins with amines are discussed as well as the conversion of the 2‐arylmalondialdehydes into 3‐chloro and 3‐alkoxyacroleins.