Premium
1,2,4‐Triazines. XII. Syntheses of 5‐carboxarnido‐1,2,4‐triazines via an addition‐oxidation reaction
Author(s) -
Krass Dennis K.,
Paudler William W.
Publication year - 1974
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570110109
Subject(s) - chemistry , potassium cyanide , cyanide , sequence (biology) , potassium , medicinal chemistry , organic chemistry , biochemistry
5‐Unsubstituted 1,2,4‐triazines, when treated with potassium cyanide suspended in moist dioxane afford 5‐carhoxamido as well as 5,5′ ‐bi‐1,2,4‐triazinyl derivatives. A probable reaction sequence is described.