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Intramolecular ring opening in 3‐aminoalkyl hydantoins
Author(s) -
Spencer Claude F.
Publication year - 1973
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570100406
Subject(s) - chemistry , intramolecular force , ring (chemistry) , stereochemistry , side chain , medicinal chemistry , organic chemistry , polymer
Certain hydantoins substituted in the 3‐position with aminoalkyl groups have been found to undergo hydrolytie ring‐opening under very mild conditions. The effects of varying the side chain have been studied and an intramolecular mechanism is suggested.