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Studies on the syntheses of heterocyclie compounds. Part DXXVII. . the absolute configuration of 1,2,3,4‐tetrahydro‐1‐phenylisoquinolines
Author(s) -
Kametani Tetsuji,
Shibuya Shiroshi,
Sugi Hideo,
Fukumoto Keiichiro
Publication year - 1973
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570100405
Subject(s) - absolute configuration , chemistry , methiodide , stereochemistry , absolute (philosophy) , base (topology) , position (finance) , mathematics , mathematical analysis , philosophy , epistemology , finance , economics
The absolute configuraiton at the C 1 ‐position of 1,2,3,4‐tetrahydro‐1‐phenylisoquinolines can be deduced from the CD curves of either the free base or its methiodide. Furthermore, the absolute con figuration of ( + )‐2‐amino‐1‐(3‐hydroxyphenyl)ethanol (V) was revised and found to have R‐configuration at the C 1 ‐position.