Premium
Synthesis of 2,2′‐bipyrimidine derivatives
Author(s) -
Feit B. A.,
Teuerslein A.
Publication year - 1973
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570100111
Subject(s) - chemistry , stereochemistry , organic chemistry
A new total synthesis of 2,2′ ‐bipyrimidine derivatives by the direct condensation of 2‐amidinopyrimidinebenzenesulfonate with dicarbonyl compounds is described. The following 2,2′‐bipyrimidines have been prepared: 5‐ethyl‐4,6‐dihydroxy‐2,2′‐bipyrimidine; 5‐ethyl‐4,6‐dichloro‐2,2 ‐bipyrimidine; 4,6‐dihydroxy‐2,2′ ‐bipyrimidine; 5‐ethyl‐4,6‐dimethoxy‐2,2′ ‐bipyrimidine.