The use of enamines in the synthesis of heterocycles | Zendy

Montgomery John A. | Zendy; Laseter Anne G. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

The use of enamines in the synthesis of heterocycles

Author(s) -

Montgomery John A.,

Laseter Anne G.

Publication year - 1972

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570090521

Subject(s) - chemistry , pyrrolidine , enamine , ring (chemistry) , pyrimidine , closure (psychology) , stereochemistry , sequence (biology) , medicinal chemistry , combinatorial chemistry , organic chemistry , catalysis , biochemistry , economics , market economy

The reaction of the enamine N ‐styryl pyrrolidine with 4,6‐dichloro‐5‐nitropyrimidine and 4‐amino‐6‐chloro‐5‐nitropyrimidine was investigated. Reduction of resultant compounds was followed by spontaneous ring closure to the pyrrolo[3,2‐ d ]pyrimidine ring system. This reaction sequence should provide a general method for the preparation of 4,7‐disubstituted pyrrolo[3,2‐ d ]‐pyrimidines.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research