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Solvent effects on the tautomeric equilibria of 4,4/5,5‐disubstituted 4 H /5 H ‐imidazol‐5/4‐ones
Author(s) -
Edward J. T.,
Lantos I.
Publication year - 1972
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570090231
Subject(s) - tautomer , chemistry , conjugated system , solvent , polar , solvent effects , computational chemistry , medicinal chemistry , photochemistry , organic chemistry , polymer , physics , astronomy
The tautomerism of 4,4/5,5‐disubstituted 4 H /5 H ‐imidazol‐5/4‐ones has been investigated by ir, uv, and p K studies. In nonpolar solvents the non‐conjugated tautomer predominates, but in polar solvents varying amounts of the conjugated tautomer may also be observed. The proportion of conjugated tautomer is increased by the presence of electron‐releasing groups at the 2‐position.