Premium
Bieyclic bases . Synthesis and stereochemical studies of chiral 5‐substituted N ‐tosyl‐2‐azabicyclo[2.2.1[ heptanes
Author(s) -
Portoghese P. S.,
Lattin D. L.,
Telang V. G.
Publication year - 1971
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570080618
Subject(s) - chemistry , stereochemistry , tosyl
The synthesis of chiral exo and endo 5‐sulbstituted N ‐losyl‐2‐azabicyclo[2.2.1]heptanes is reported. The nearly identical exo‐endo equilibrium ratios of the title compounds and the carbocyclic analogs suggest that their geometries and sterie interactions are quite similar.