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Synthesis of some N ‐substituted 6,7‐dimethoxy‐1,2‐benzothiazin(4 H )‐3‐one 1,1‐dioxides
Author(s) -
Catsoulacos P.
Publication year - 1971
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570080611
Subject(s) - chemistry , ammonia , primary (astronomy) , chloride , medicinal chemistry , organic chemistry , liquid ammonia , physics , astronomy
Substituted 1,2‐benzothiazin‐3‐ones have been prepared by cyclization of 4,5‐dimethoxy‐2‐carboethoxymethybenzenesulfonamides. The latter were obtained by the action of ammonia and primary and secondary amines on 4,5‐dimethoxy‐2‐carboethoxymethylbenzenesulfonyl chloride which in turn was obtained from ethyl 3,4‐dimethoxyphenylacetate and chlorosulfonic acid.