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Isothiazoles IV: 4‐isothiazolin‐3‐one i‐oxide and 1,1‐dioxides
Author(s) -
Lewis S. N.,
Miller G. A.,
Hausman M.,
Szamborski E. C.
Publication year - 1971
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570080411
Subject(s) - chemistry , nitric acid , oxide , nitric oxide , organic chemistry
Representative 4‐isothiazolin‐3‐one I‐oxides and I, I‐dioxides have been prepared by the reaction of m ‐chloroperbenzoic acid with the respective 4‐isothiazolin‐3‐ones. Chromic acid, dinitrogen tetroxide, and nitric acid have also been successfully employed in the oxidation of several 3‐hydroxyisothiazoles to their respective I‐oxides.