Premium
1,2,3,5‐Tetrahydro‐4 H ‐1,5‐benzodiazepin‐4‐ones and 1,2,3,4‐tetrahydro‐5 H ‐1,4‐benzodiazepin‐5‐ones from the reaction of hydrazoic acid on 1,2,3,4‐tetrahydroquinolin‐4‐ones
Author(s) -
Misiti D.,
Gatta F.,
LandiVittory R.
Publication year - 1971
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570080209
Subject(s) - chemistry , nitrogen atom , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry
The Schmidt reaction on 1,2,3,4‐telrahydroquinolin‐4‐ones (1) gave 1,2,3,5‐telrahydro‐l,5‐benzodiazepin‐4‐ones (II) and 1,2,3,4‐tetrahydro‐1,4‐benzodiazepin‐5)‐ones(III). The ratio of II and III is dependent upon substituents present on the nitrogen ring atom of the quinolinones.