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The amidoalkylation of aromatic compounds and olefins with 5‐alkoxyhydantoins
Author(s) -
BenIshai D.,
BenEt G.,
Warshawsky A.
Publication year - 1970
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570070609
Subject(s) - chemistry , double bond , catalysis , hydantoin , organic chemistry , medicinal chemistry
5‐Butoxyhydantoin (2a), 3‐benzyl‐5‐methoxyhydantoin (2b) and 3‐ p ‐chlorophenyl‐5‐methoxy hydantoin (2c) were found to react, in the presence of an acid catalyst, with aromatic compounds and olefins to give 5‐arylhydantoin (3) and 5‐alkylhydantoins with an unsaturated side chain. Isomers which differ in the location of the double bond (4,5,6) as well as cis‐trans isomers were isolated and characterized.
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