Premium
Synthesis of 4‐azatricyclo[4.3.1.1 3,8 ] undecane (4‐azahomoadamantane)
Author(s) -
Narayanan V. L.,
Setescak L.
Publication year - 1970
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570070414
Subject(s) - undecane , chemistry , beckmann rearrangement , lactam , hydrochloride , stereochemistry , medicinal chemistry , organic chemistry , oxime
Efficient routes for the synthesis of 4‐azahomoadamantane (V) via the Beckmann and Schmidt rearrangements are described. The lactam III is unusual in that it forms a stable crystalline hydrochloride IV.