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Studies on the syntheses of azole derivatives. Part III . Syntheses of 1‐Phenyl‐Δ 2 ‐1,2,4‐triazolin‐5‐one and 4‐Phenyl‐Δ 2 ‐1,3,4‐oxadiazolin‐5‐one Derivatives by Fusion of 1‐Phenyl‐2‐acylhydrazine with Urea
Author(s) -
Kametani Tetsuji,
Sota Kaoru,
Shio Masahisa
Publication year - 1970
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570070411
Subject(s) - chemistry , azole , urea , medicinal chemistry , organic chemistry , antifungal , dermatology , medicine
Fusion of 1‐phenyl‐2‐acylhydrazine (III) with urea gave Δ 2 ‐1,2,4‐triazolin‐5‐one and Δ 2 ‐1,3,4‐oxadiazolin‐5‐one derivatives together with various by‐products. Furthermore, various derivatives were synthesized for the purpose of examination in a pharmacological screening test.
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