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Mass spectra of some aminonaphthyridines and aminoquinolines
Author(s) -
Brown Ellis V.,
Plasz Andrew C.,
Mitchell Stanley R.
Publication year - 1970
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570070330
Subject(s) - chemistry , fragmentation (computing) , aminoquinolines , mass spectrum , ion , polyatomic ion , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , computer science , operating system
The mass spectra of all the aminoquinolines, the 2–, 3– and 4‐amino‐1,5‐naphthyridines, some amino‐1,6‐naphthyridines, and two amino‐1,8‐naphthyridines with methyl substituents are reported. The major fragment in the aminoquinolines is formed by the loss of HCN from the molecular ion. The most abundant fragment in the aminonaphthyridines is formed by the loss of HCN from the molecular ion except in the 2‐amino‐1,5‐naphthyridine isomer. In both 1,8‐naphthyridine isomers investigated, the loss of C 2 H 2 is an alternate fragmentation pathway of significance. In all of the compounds investigated, the loss of the primary amino group from the molecular ion was found to be an insignificant fragmentation.