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A study of some 1‐alkyl‐2,3‐dihydroimidazo[1,2‐a]benzimidazoles
Author(s) -
North Robert J.,
Day Allan R.
Publication year - 1969
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570060511
Subject(s) - chemistry , alkylation , alkyl , electrophile , tautomer , medicinal chemistry , nitro , organic chemistry , catalysis
A series of 1‐alkyl‐7‐nitro (and 7‐amino)‐2,3‐dihydroimidazo[1,2‐α]benzimidazoles has been prepared. Similarly, a series of 1‐alkyl‐2,3‐dihydroimidazo[1,2‐α]benzimidazoles has been prepared. The prototropic tautomerism of this system has been studied. The site of electrophilic attack (alkylation) has been examined. 1‐Alkylation takes place under strongly basic conditions and 9‐alkylation occurs under neutral conditions.