Premium
Ring closure reactions with nitriles. III. Formation of 2‐amino‐ and 2‐oxo‐3‐hydroxyindoles from the reaction of 2′‐aroylacylanilides with cyanide
Author(s) -
Bell Stanley C.,
Wei Peter H. L.
Publication year - 1969
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570060501
Subject(s) - chemistry , closure (psychology) , cyanide , ring (chemistry) , medicinal chemistry , organic chemistry , market economy , economics
Treatment of 2′‐aroylhaloacylanilides with potassium cyanide produced quinazolines, carbostyrils, and 3‐hydroxyindoles. From the reaction of 2′‐aroyl‐2,2‐dichloroacetanilides with cyanide, good yields of 2‐amino‐3‐hydroxyindoles were obtained and their reactions were studied.