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Diazepines. VI. The chemistry of 3,8‐dihalo‐11 H ‐dibenzo[c, f ] [1,2]diazepin‐11‐ones
Author(s) -
Popp Frank D.,
Dubois Ronald J.,
Casey Adria Catala
Publication year - 1969
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570060303
Subject(s) - chemistry , carbonyl group , ketone , hydrazine (antidepressant) , medicinal chemistry , group (periodic table) , inert , organic chemistry , chromatography
The carbonyl group in the title compounds undergoes a number of reactions typical of ketones but in general is less reactive than a typical ketone. Reaction with hydrazine leads to reduction of the 5,6‐bond rather than reaction at the carbonyl group. Reduction of the carbonyl group gives rise to a rather inert carbinol. The carbonyl group appears to exert little influence on typical reactions at the 5,6‐position.