Premium
Ring‐opening nucleophilic alkylations by tertiary azetidines
Author(s) -
Gaertner V. R.
Publication year - 1969
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570060301
Subject(s) - chemistry , nucleophile , reagent , ring (chemistry) , catalysis , medicinal chemistry , organic chemistry , combinatorial chemistry
N ‐Alkylazetidines were cleaved by nucleophilic reagents under moderate conditions to give the corresponding 3‐substituted‐propylamines. The additions were subject to acid catalysis and also proceeded slowly under alkaline S N 2conditions.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom