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The synthesis of lmidazo[4,5‐ d ] pyridazines. VI. v ‐Triazolo[4,5‐ d ] pyridazines, pyrazino[ 2,3‐ d ] pyridazines and 7 H ‐Imidazo [4,5‐ d ] tetrazolo[ 1,5‐ b ] pyridazine
Author(s) -
Martin Stephen F.,
Castle Raymond N.
Publication year - 1969
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570060116
Subject(s) - chemistry , pyridazine , ring (chemistry) , stereochemistry , medicinal chemistry , computational chemistry , organic chemistry
Several pyridazines have been prepared as intermediates in the synthesis of monosubstituted imidazo[4,5‐ d ]pyridazines, monosubstituted v ‐triazoIo[4,5‐ d ]pyridazines and monosubstituted pyrazino [2,3 d ] pyridazines. The new ring system, 7 H ‐imidazo[4,5‐ d ]tetrazolo[l,5‐ b ] pyridazine (XIV) has been prepared unsubstituted. Furthermore, unsubstituted imidazo[4,5‐ d ]pyridazine (XI) has been prepared. Calculations for XI and XIV were made by approximate SCF LCAO‐MO with CNSO II theory.