Steroid derivatives of purine‐6(1 H )‐thione (1a‐c) | Zendy

Carroll F. I. | Zendy; Philip Abraham | Zendy; Ferguson Anna M. | Zendy; Wall Monroe F. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Steroid derivatives of purine‐6(1 H )‐thione (1a‐c)

Author(s) -

Carroll F. I.,

Philip Abraham,

Ferguson Anna M.,

Wall Monroe F.

Publication year - 1968

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570050612

Subject(s) - chemistry , alkylation , purine , steroid , purine metabolism , stereochemistry , medicinal chemistry , organic chemistry , biochemistry , enzyme , hormone , catalysis

The products obtained as a result of the alkylation of purine‐6(1 H )‐thione, and 6‐alkylthiopurines with steroidal‐21‐( p ‐bromobenzenesullonates) (H) and 3‐methoxy‐16α‐bromoestra‐1,3,5 (10)‐tricne‐17‐one (IV) is reported. The ratio of 9‐alkylated to 7‐alkylated purine in the alkylation of 6‐methylthiopurine (VI) is presented. The use of the S ‐diphenylmethylprotecling group in the syntheses of sensitive 9‐steroidal‐9 H ‐purine‐6(1 H )‐thiones is discussed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research