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Phthalonimides (1,3,4‐trioxo‐1,2,3,4‐tetrahydroisoquinolines) of potential biological interest
Author(s) -
BuuHoï N. P.,
SaintRuf G.,
Bourgeade J. C.
Publication year - 1968
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570050416
Subject(s) - chemistry , selenium , combinatorial chemistry , organic chemistry
A new simple method for the preparation of phthalonimides (1,3,4‐trioxo‐1,2,3,4‐tetrahydroisoquinolines), consisting of the selenium dioxide‐oxidation of the appropriate homophthalimides, has been devised; the thiosemicarbazones and other derivatives of phthalonimides of possible biological interest (as potential antibacterial, antiviral, or immunosuppressive agents) have been synthesized.