Friedel crafts reactions of three‐member ileterocycles II: Alkylation of aromatic compounds with aziridines | Zendy

Milstein Norman | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Friedel crafts reactions of three‐member ileterocycles II: Alkylation of aromatic compounds with aziridines

Author(s) -

Milstein Norman

Publication year - 1968

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570050307

Subject(s) - chemistry , friedel–crafts reaction , chlorobenzene , toluene , substituent , phenethylamine , aziridine , alkylation , benzene , medicinal chemistry , chloride , organic chemistry , catalysis , ring (chemistry) , stereochemistry

The Friedel Crafts reaction of propylenimine with symmetrical arenes in the presence of aluminum chloride was investigated. Electron donating substituents increase the α‐methyl‐β‐phenethylamine/ β‐methyl‐β‐phenethylaimine ratio, while increasing the temperature has the opposite effect. In the reaction of chlorobenzene or toluene with aziridine, the nature of the substituent has little effect on the ortho/para ratio.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research