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Oxazolidine formation in the attempted eschweiler‐clarke reductive methylation of cis ‐3‐aminobicyclo[2.2.2] octan‐2‐ol
Author(s) -
Nelson Wendel L.
Publication year - 1968
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570050214
Subject(s) - chemistry , oxazolidine , stereochemistry
Evidence is presented confirming the formation of N ‐methyl‐ cis ‐bicyclo[2.2.2]octyl[2,3‐ d ]‐oxazolidine as the product of Eschweiler‐Clarke reductive alkylation of cis ‐3‐amino‐bicyclo‐[2.2.2]octan‐2‐ol.