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1‐(2‐Mercaptoethyl)phthalazines and related compounds
Author(s) -
Castle Raymond N.,
Takano Seiichi
Publication year - 1968
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570050115
Subject(s) - chemistry , phthalazine , propane , bromide , medicinal chemistry , sodium bromide , sodium , organic chemistry
1‐(2‐Mercaptoethyl)phthalazine (VII) and its analogs such as S ‐2‐(1‐phthalazyl)ethyliso‐thiuronium bromide (VI), sodium S ‐2‐(1‐phthalazyl)ethylthiosulfate (VIII), 1,3‐bis‐acetylthio‐2‐(1‐phthalazyl)propane (XII), 2‐(1‐phthalazyl)‐1,3‐propanedithiol (XIII), disodium 2‐(1‐phthalazyl)‐1,3‐propanedithiosulfate (XIV), 3‐dimethylamino‐2‐(1‐phthalazyl)‐1‐propanethiol (XVII) and 3‐(4‐methyl‐1‐piperazinyl)‐2‐(1‐phthalazyl)‐1‐propanethiol (XIX) have been prepared as potential radiation protection agents.