1‐(2‐Mercaptoethyl)phthalazines and related compounds | Zendy

Castle Raymond N. | Zendy; Takano Seiichi | Zendy

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1‐(2‐Mercaptoethyl)phthalazines and related compounds

Author(s) -

Castle Raymond N.,

Takano Seiichi

Publication year - 1968

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570050115

Subject(s) - chemistry , phthalazine , propane , bromide , medicinal chemistry , sodium bromide , sodium , organic chemistry

1‐(2‐Mercaptoethyl)phthalazine (VII) and its analogs such as S ‐2‐(1‐phthalazyl)ethyliso‐thiuronium bromide (VI), sodium S ‐2‐(1‐phthalazyl)ethylthiosulfate (VIII), 1,3‐bis‐acetylthio‐2‐(1‐phthalazyl)propane (XII), 2‐(1‐phthalazyl)‐1,3‐propanedithiol (XIII), disodium 2‐(1‐phthalazyl)‐1,3‐propanedithiosulfate (XIV), 3‐dimethylamino‐2‐(1‐phthalazyl)‐1‐propanethiol (XVII) and 3‐(4‐methyl‐1‐piperazinyl)‐2‐(1‐phthalazyl)‐1‐propanethiol (XIX) have been prepared as potential radiation protection agents.

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