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5,6‐dihydro‐4H‐1,3,4‐thiadiazines. II. synthesis and use of 1‐(1‐methylhydrazino)‐2‐propanethiol for the preparation of various thiadiazines and a 2‐thiazolidinethione
Author(s) -
Trepanier D. L.,
Krieger P. E.
Publication year - 1967
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570040215
Subject(s) - chemistry , triethyl orthoformate , benzonitrile , yield (engineering) , bromide , carbon disulfide , benzaldehyde , organic chemistry , medicinal chemistry , chloride , condensation , catalysis , materials science , thermodynamics , metallurgy , physics
This paper reports the synthesis of 1‐(1‐methylhydrazino)‐2‐propanethiol and the results of a study of its reactions with benzaldehyde, benzonitrile, benzoyl chloride, triethyl orthoformate, succinonitrile, cyanogen bromide, and cyclopropylcyanide to give a thiadiazine directly or a product which can be converted to a thiadiazine. It also reports the condensation of 1‐(1‐methylhydrazino)‐2‐propanethiol with carbon disulfide to yield a 2‐thiazolidinethione.