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N ‐Heteroaralkyl substituted α‐amidinium thiolsulfates
Author(s) -
Parulkar Anilkumar P.,
Bauer Ludwig
Publication year - 1966
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570030417
Subject(s) - chemistry , amidine , medicinal chemistry , stereochemistry
The syntheses of a number of N ‐substituted α‐amidinium thiolsulfates, CH 2 (S 2 O 3 − )‐C(=NH 2 + )NH(CH 2 )nR are described, where n was varied from 1 to 3 and R represents such heteroaryl groups as 2‐furyl, 2‐thienyl, 3‐indolyl and 2‐, 3‐ and 4‐pyridyl. The preparation of S ‐(2‐imidazolinemethyl)thiolsulfuric acid, as an example of an N, N' ‐disubstituted α‐amidinium thiolsulfate, is also reported.