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The synthesis of 1,4,5‐trialkyl‐2‐pyrazolines from monoalkylhydrazines and aliphatic aldehydes
Author(s) -
Rabjohn Norman,
Havens H. R.,
Rutter J. L.
Publication year - 1966
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570030404
Subject(s) - chemistry , heptanal , methylamine , thermal decomposition , pyrazoline , organic chemistry , decomposition , aldehyde , catalysis
It has been found that the thermal decomposition of heptanal methylhydrazone affords 5‐hexyl‐1‐methyl‐4‐pentyl‐2‐pyrazoline (I), in addition to heptanenitrile and methylamine. The formation of I suggests the synthesis of 1,4, 5‐trialkyl‐2‐pyrazolines from monoalkylhydrazines and aliphatic aldehydes. A number of these compounds have been prepared in good yields by this method, or through the related hydrazones, and some of their physical and chemical properties have been studied.