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A new synthesis of alkyl and aryl 2‐aminoimidazoles
Author(s) -
Lancini Gian Carlo,
Lazzari Ettore
Publication year - 1966
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570030208
Subject(s) - chemistry , cyanamide , alkyl , aryl , condensation , organic chemistry , medicinal chemistry , combinatorial chemistry , physics , thermodynamics
The condensation of cyanamide with α‐aminocarbonyl compounds has been studied as a method of synthesizing alkyl and aryl 2‐aminoimidazoles. Starting from N ‐alkylamino‐aldehydes, 1,5‐dialkyl‐2‐aminoimidazoles have been prepared. Starting from suitable aminoketones a variety of monosubstituted and disubstituted derivatives were obtained.